Napoli have faced difficulties since the departure of Khvicha Kvaratskhelia, and Antonio Conte’s tactical adjustments have yet to deliver results. Their 2-1 loss to Como extended their winless run to four matches, raising concerns about their title ambitions. They will be without Mazzocchi, Anguissa, and David Neres due to injuries. Conte is expected to stick with a 3-5-2 formation, with Lukaku and Raspadori leading the attack. Inter Milan come into this match after a 2-0 Coppa Italia victory over Lazio but have suffered injuries to Matteo Darmian and Nicola Zalewski. They are also missing goalkeepers Yann Sommer and Raffaele Di Gennaro. Despite these setbacks, Simone Inzaghi’s side remains strong at the top of the table, with Lautaro Martinez and Taremi expected to start up front.

Napoli’s poor form and Inter’s defensive stability suggest a tense and low-scoring match. While Napoli need a positive result to stay in the title race, Inter’s consistency gives them a slight edge. With both teams likely to approach the game cautiously, a match with fewer than 2.5 goals seems the most probable outcome.