Enzo Maresca is expected to rotate his squad, balancing the need to protect key players ahead of the weekend's Premier League clash with Newcastle. Youngsters Josh Acheampong, Tyrique George, and Shumaira Mheuka are all likely to feature, while Christopher Nkunku remains sidelined alongside Wesley Fofana and Marc Guiu. Romeo Lavia, recently fit again, is ineligible for the Conference League.
Djurgarden are dealing with a lengthy absentee list, including first-choice goalkeeper Filip Manojlovic and several unregistered or injured key players. Jacob Rinne will continue in goal, with Jani Honkavaara forced to rely on a depleted squad again, after naming just seven substitutes in the first leg.
Chelsea 2-1 Djurgardens IF
While Chelsea are unlikely to dazzle, their superior depth and confidence should see them secure a routine win. Djurgardens have done remarkably to reach this stage, but with a stretched squad and an uphill battle ahead, even a consolation result in London looks beyond reach.